Yes, it's possible to travel from Aswan to Cairo by plane and then visit the Giza Pyramids, which are located on the outskirts of Cairo.
Flights between Aswan and Cairo are available, and once you arrive in Cairo, you can arrange ground transportation—such as taxis, private cars, or guided tours—to reach the Giza Plateau where the famous Giza Pyramids and the Great Sphinx are located.
The distance between Aswan and Cairo by air is relatively short, and flights typically take around 1-1.5 hours. However, it's important to consider the additional travel time and arrangements required to reach Giza from Cairo once you land.